Oral acyclovir in treatment of suspected herpes simplex encephalitis.

izing signs. In survivors, it frequently produces severe sequelae(2). Intravenous acyclovir is currently the drug of choice for HSE and it substantially reduces the mortality and morbidity(2). We could* not come across any reports of trials of oral acyclovir in the treatment of HSE. We report here, a case of suspected herpes simplex encephalitis, which responded dramatically to oral acyclovir therapy. The cost of 10 days treatment of a 25 Kg child with intravenous therapy drug is Rs. 21,000/-, while it is only Rs. 750 with oral therapy.